Synovial Fluid Cytokines, Chemokines and MMP Levels in Osteoarthritis Patients with Knee Pain Display a Profile Similar to Many Rheumatoid Arthritis Patients.
Richard Thomas MeehanElizabeth A ReganEric D HoffmanMolly L WolfMary T GillJames L CrooksPrashant J ParmarRichard A ScheuringJohn C HillKarin A PachecoVijaya KnightPublished in: Journal of clinical medicine (2021)
These results support the growing evidence that OA patients have a pro-inflammatory/catabolic SF environment. SF biomarker analysis using multiplex testing and US guidance may distinguish OA phenotypes and identify treatment options based upon targeted inflammatory pathways similar to patients with RA.
Keyphrases
- rheumatoid arthritis patients
- knee osteoarthritis
- end stage renal disease
- disease activity
- rheumatoid arthritis
- chronic kidney disease
- newly diagnosed
- chronic pain
- peritoneal dialysis
- oxidative stress
- total knee arthroplasty
- pain management
- neuropathic pain
- systemic lupus erythematosus
- spinal cord
- spinal cord injury
- ankylosing spondylitis
- real time pcr