Downregulation of Talin-1 is associated with the increased expression of miR-182-5p and miR-9-5p in coronary artery disease.
Akram GholipourFarshad ShakerianAli ZahedmehrShiva IraniSeyed Javad MowlaMahshid MalakootianPublished in: Journal of clinical laboratory analysis (2022)
Our findings demonstrated that miR-182-5p and miR-9-5p could play significant roles in TLN1 regulation and participate in CAD development by targeting TLN1. These findings introduce novel biomarkers with a potential role in CAD pathogenesis.