Notch and Bmp signaling pathways act coordinately during the formation of the proepicardium.
Laura Andrés-DelgadoMaría Galardi-CastillaJuliane MünchMarina PeraltaAlexander ErnstJuan Manuel González-RosaFederico TessadoriLuis SantamaríaJeroen BakkersJulien VermotJosé Luis de la PompaNadia MercaderPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
Endothelial Notch signaling activates bmp expression in the heart tube, which in turn induces PE cluster formation from the DP layer.