HLA-based banking of induced pluripotent stem cells in Saudi Arabia.

Maryam AlowaysiRobert LehmannMohammad Al-ShehriMoayad BaadhaimHajar AlzahraniDoaa AboalolaAsima ZiaDalal MalibariMustafa DaghestaniKhaled AlghamdiAli HaneefDunia JawdatFahad HakamiDavid Gomez-CabreroJesper TegnerKhaled Alsayegh

Published in: Stem cell research & therapy (2023)

Our study sets a road map for introducing iPS-based cell therapy in the Kingdom of Saudi Arabia. It underscores the pragmatic approach of HLA-based iPSC banking which circumvents the limitations of autologous iPS-based cellular therapies. The successful generation and validation of iPSC lines based on the most prevalent HLA haplotype in the Saudi population signify a promising step toward broadening the accessibility and applicability of stem cell therapies and regenerative medicine in Saudi Arabia.

Keyphrases

cell therapy
induced pluripotent stem cells
saudi arabia
stem cells
mesenchymal stem cells
study protocol
bone marrow
randomized controlled trial
high density
platelet rich plasma