GLUT1 expression in high-risk prostate cancer: correlation with 18F-FDG-PET/CT and clinical outcome.
Salma MeziouCassandra Ringuette GouletHélène HovingtonVéronique LefebvreÉtienne LavalléeMichelle BergeronHervé BrissonAudrey ChampagneBertrand NeveuDidier LacombeJean-Mathieu BeauregardFrançois-Alexandre ButeauJulie RiopelFrédéric PouliotPublished in: Prostate cancer and prostatic diseases (2020)
GLUT1 expression in PCa tumours correlates with 18F-FDG-uptake and poor prognostic factors. These results suggest that this transporter is involved in the molecular mechanism of 18F-FDG-uptake in high-risk PCa and raise interest in targeting metabolic dependencies of PCa cells as a selective anticancer strategy.