Extracellular vesicles in plasma and cerebrospinal fluid in patients with COVID-19 and neurological symptoms.

Apostolos TaxiarchisBo-Michael BellanderJovan AntovicNida SoutariJohan VirhammarEva KumlienCan KarakoyunElham RostamiAleksandra Antovic

Published in: International journal of laboratory hematology (2023)

The unique finding in this study was the presence of EVs in the CSF of COVID-19 patients with neurologic manifestations as well as higher expression of complement protein on circulating plasma EVs. EVs may indicate blood-brain barrier damage during SARS-COV-2 infection.

Keyphrases

blood brain barrier
cerebrospinal fluid
cerebral ischemia
coronavirus disease
sars cov
poor prognosis
binding protein
oxidative stress
respiratory syndrome coronavirus
sleep quality
depressive symptoms