Exchange transfusion for hemolytic hyperbilirubinemia: could some be averted by emergent administration of an inhibitor of bilirubin production?

Susan E WiedmeierTimothy M BahrRobin K OhlsThomas R ChristensenVickie L BaerSarah J IlstrupKelly CailRobert D Christensen

Published in: Journal of perinatology : official journal of the California Perinatal Association (2020)

A trial testing compounds that can inhibit bilirubin production would have about three eligible neonates/years in our system. Since our births are 1% of national, up to 300 neonates/years might qualify for such a study.

Keyphrases

low birth weight
clinical trial
cardiac surgery
study protocol
phase iii
quality improvement
phase ii
randomized controlled trial
preterm infants
gestational age
preterm birth
acute kidney injury
open label
double blind