Single-Cell Phenotypic and Molecular Characterization of Circulating Tumor Cells Isolated from Cryopreserved Peripheral Blood Mononuclear Cells of Patients with Lung Cancer and Sarcoma.

Marta VismaraCarolina ReduzziMarco SilvestriFabio MurianniGiuseppe Lo RussoOrazio FortunatoRosita MottaDavide LanzoniFrancesca GiovinazzoPatrizia MiodiniSandro PasqualiPaola SuatoniUgo PastorinoLuca RozGabriella SozziVera CappellettiGiulia Bertolini

Published in: Clinical chemistry (2022)

Isolating CTCs from longitudinally collected PBMCs using an unbiased selection strategy can offer a wider range of retrospective genomic/phenotypic analyses to guide patients' personalized therapy, paving the way for sample sharing in multicenter studies.

Keyphrases

circulating tumor cells
end stage renal disease
single cell
newly diagnosed
chronic kidney disease
cross sectional
circulating tumor
rna seq
prognostic factors
peritoneal dialysis
social media
high throughput
copy number
health information
dna methylation
cord blood
cell free
chemotherapy induced