Gait alterations associated with worsening knee pain and physical function: a machine-learning approach with wearable sensors in the Multicenter Osteoarthritis Study.

We identified gait alterations associated with worsening knee pain and those associated with worsening physical function. These alterations could be assessed with wearable sensors in clinical settings. Further research should determine whether they might be therapeutic targets to prevent worsening pain and worsening function.