Cognitive dysfunction in amyotrophic lateral sclerosis: can we predict it?

Fabiola De MarchiClaudia CarrariniAntonio De MartinoLuca DiamantiAntonio FasanoAntonino LupicaMirella RussoSimone SalemmeEdoardo Gioele SpinelliAlessandro Bombacinull null

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)

To date, the research on humoral, radiological, neurophysiological, and genetic correlates of neuropsychological alterations is at the early stage, and no conclusive longitudinal data have been published. Further and longitudinal studies on easily accessible and quantifiable biomarkers are needed to clarify the time course and the evolution of cognitive and behavioral impairments of ALS patients.

Keyphrases

early stage
end stage renal disease
immune response
ejection fraction
newly diagnosed
chronic kidney disease
cross sectional
peritoneal dialysis
squamous cell carcinoma
systematic review
genome wide
big data
electronic health record
patient reported outcomes
radiation therapy