The severity of rat liver injury by fructose and high fat depends on the degree of respiratory dysfunction and oxidative stress induced in mitochondria.
Claudia Isabel García-BerumenOmar Ortiz-AvilaManuel Alejandro Vargas-VargasBricia A Del Rosario-TamayoClotilde Guajardo-LópezAlfredo Saavedra-MolinaAlain Raimundo Rodríguez-OrozcoChristian Cortés-RojoPublished in: Lipids in health and disease (2019)
Severity of liver injury induced by fructose or fat was related to the degree of dysfunction and oxidative damage in mitochondria. Attention should be paid on the serious effects observed in the HF + Fr group as the typical Western diet is rich in both fat and carbohydrates.