Kidney Disease, Intensive Hypertension Treatment, and Risk for Dementia and Mild Cognitive Impairment: The Systolic Blood Pressure Intervention Trial.
Manjula Kurella TamuraSarah A GaussoinNicholas M PajewskiGordon J CheluneBarry I FreedmanTanya R GureWilliam E HaleyAnthony A KilleenSuzanne OparilStephen R RappDena E RifkinMark SupianoJeff D WilliamsonDaniel E Weinernull nullPublished in: Journal of the American Society of Nephrology : JASN (2020)
Among hypertensive adults, declining kidney function measured by eGFR is associated with increased risk for probable dementia and MCI, independent of the intensity of hypertension treatment.
Keyphrases
- mild cognitive impairment
- blood pressure
- cognitive decline
- hypertensive patients
- heart rate
- small cell lung cancer
- randomized controlled trial
- clinical trial
- heart failure
- cognitive impairment
- type diabetes
- epidermal growth factor receptor
- skeletal muscle
- high intensity
- combination therapy
- metabolic syndrome
- insulin resistance
- replacement therapy
- phase ii
- smoking cessation