Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma.

Annika Hohm Michael Karremann Gerrit H Gielen Torsten Pietsch Monika Warmuth-Metz Lindsey A Vandergrift Brigitte Bison Annika Stock Marion Hoffmann Mirko Pham Christof Maria Kramm Johannes Nowak

Published in: Clinical neuroradiology (2021)

With this study, we are the first to provide detailed MR imaging data on H3 K27M mutant pDMG with respect to molecular subgroup status in a large patient cohort. Our findings may support diagnosis and future targeted therapeutic trials of pDMG within the framework of the radiogenomics concept.

Keyphrases

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cancer therapy
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randomized controlled trial
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machine learning
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