Distinct patterns of myogenic motor activity identified in isolated human distal colon with high-resolution manometry.
Reizal M RosliPaul T HeitmannRaghu KumarTim J HibberdMarcello CostaLukasz WiklendtDavid A WattchowJohn William ArkwrightDayan de FontgallandSimon S J BrookesNick J SpencerPhilip G DinningPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
Our study suggests that the propagated contractions recorded in the organ bath have a myogenic origin which can be regulated by neural input. Once activated at a local site, the contractions do not require the propulsion of fecal content to sustain long-distance propagation.