Frailty, Cognitive Impairment, and Anticoagulation Among Older Adults with Nonvalvular Atrial Fibrillation.
Tanya MailhotDavid D McManusMolly E WaringDarleen LessardRobert GoldbergBenita A BamgbadeJane S SaczynskiPublished in: Journal of the American Geriatrics Society (2020)
In a large cohort of older NVAF patients, half were frail or cognitively impaired, and 9% had both impairments. We highlight the characteristics of patients who may benefit from cognitive and physical function screenings to maximize treatment and enhance prognosis. Finally, the co-occurrence of impairment was associated with low perceived benefit of treatment that may impede optimal management.
Keyphrases
- atrial fibrillation
- cognitive impairment
- community dwelling
- end stage renal disease
- physical activity
- ejection fraction
- depressive symptoms
- direct oral anticoagulants
- oral anticoagulants
- newly diagnosed
- heart failure
- left atrial appendage
- mental health
- venous thromboembolism
- catheter ablation
- left atrial
- combination therapy
- cognitive decline
- middle aged
- social support
- peritoneal dialysis
- mild cognitive impairment
- mitral valve
- patient reported outcomes
- percutaneous coronary intervention
- replacement therapy
- left ventricular