Combined Ibuprofen-Nanoconjugate Micelles with E-Selectin for Effective Sunitinib Anticancer Therapy.

Xianhu ZengYi TengChunrong ZhuZhi-Peng LiTian LiuYong Sun Shangcong Han

Published in: International journal of nanomedicine (2022)

The SPI/SU nanomicelles displayed excellent anti-tumor ability, and can suppress the metastasis of tumor cell by decreasing the expression of Cyclooxygenase-2 due to the ibuprofen, providing an optimistic clinical application potential by developing a simple but safe drug delivery system.

Keyphrases

poor prognosis
drug delivery
cell therapy
single cell
postoperative pain
renal cell carcinoma
cancer therapy
drug release
binding protein
metastatic renal cell carcinoma
nitric oxide synthase
human health
long non coding rna
mesenchymal stem cells
climate change
bone marrow
replacement therapy
smoking cessation