Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model.

Ningxun CuiMingling CuiJie LiXueping Zhu Xiaoli Zhu

Published in: Gastroenterology research and practice (2020)

IRE1α was induced in PNALD cell model and suppression of IRE1α resulted in reduced steatosis in this cell disease model. Taken together, our data suggested that the IRE1α pathway may be involved in the development of PNALD.α signal in the process of PNALD. α signal in the process of PNALD. α signal in the process of PNALD.

Keyphrases

endoplasmic reticulum stress
single cell
cell therapy
stem cells
metabolic syndrome
insulin resistance
type diabetes
oxidative stress
big data
bone marrow
deep learning
fatty acid
diabetic rats