HLA-G 3' untranslated region polymorphic sites associated with increased HLA-G production are more frequent in patients exhibiting differentiated thyroid tumours.
Nathalie Lobo de Figueiredo-FeitosaGustavo Martelli PalominoDaiani Cristina Cilião AlvesCelso Teixeira Mendes-JuniorEduardo Antonio DonadiLéa Maria Zanini MacielPublished in: Clinical endocrinology (2017)
HLA-G 3'UTR polymorphisms associated with a greater magnitude of HLA-G production were associated with differentiated thyroid tumours and with variables implicated in poor prognosis. These findings corroborate the unfavourable role of HLA-G in thyroid cancer.