Unravelling relationships between obesity, diabetes, and factors related to somatosensory functioning in knee osteoarthritis patients.
Lotte MeertSophie VervullensChristiaan H W HeusdensRob J E M SmeetsMira MeeusMichel G C A M MertensPublished in: Clinical rheumatology (2024)
The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA. However, no significant correlations were found between BMI or HbA1c levels and pain-related outcomes. Future research should focus on longitudinal studies to elucidate the causal relationships and further explore the impact of metabolic factors on pain mechanisms in this patient population. Key Points • The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA.
Keyphrases
- knee osteoarthritis
- chronic pain
- type diabetes
- adipose tissue
- transcranial direct current stimulation
- pain management
- end stage renal disease
- neuropathic pain
- metabolic syndrome
- newly diagnosed
- ejection fraction
- cardiovascular disease
- total knee arthroplasty
- insulin resistance
- weight gain
- body mass index
- fatty acid
- glycemic control
- prognostic factors
- case report
- spinal cord injury
- physical activity
- postoperative pain