Metagenomic Analysis of the Pediatric-Onset Multiple Sclerosis Gut Microbiome.
Ali I MirzaFeng ZhuNatalie KnoxJessica D ForbesGary Van DomselaarCharles N BernsteinMorag GrahamRuth Ann MarrieJanace HartE Ann YehDouglas L ArnoldAmit Bar-OrJulia O'MahonyYinshan ZhaoWilliam HsiaoBrenda BanwellEmmanuelle WaubantHelen TremlettPublished in: Neurology (2021)
and depletion of the lactate fermentation pathway. DMD exposure was associated with butyrate-producing enzyme enrichment. Together these findings indicate that the gut microbiome of individuals with MS may have a disturbed functional potential.