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The transcriptome profile of human trisomy 21 blood cells.

Francesca AntonarosRossella ZenatelliGiulia GuerriMatteo BertelliChiara LocatelliBeatrice VioneFrancesca CatapanoAlice GoriLorenza VitaleMaria Chiara PelleriGiuseppe RamacieriGuido CocchiPierluigi StrippoliMaria CaracausiAllison Piovesan
Published in: Human genomics (2021)
The alteration of these pathways might be linked and involved in the manifestation of ID in DS.
Keyphrases
  • induced apoptosis
  • endothelial cells
  • cell cycle arrest
  • gene expression
  • rna seq
  • single cell
  • induced pluripotent stem cells
  • genome wide
  • pluripotent stem cells
  • oxidative stress
  • signaling pathway
  • pi k akt