Efficacy and Tolerability of Tenofovir Disoproxil Fumarate Based Regimen as Compared to Zidovudine Based Regimens: A Systematic Review and Meta-Analysis.

Tegene Legese Dadi Adane Teshome KefaleTeshale Ayele MegaMuktar Sano KedirHabtamu Acho AddoTessema Tsehay Biru

Published in: AIDS research and treatment (2017)

The use of TDF/FTC/EFV as first line regimen for naïve HIV-1 infected adult patient showed superior viral load suppression and tolerability as compared to ZDV/3TC/EFV. In order to compare the death outcome of both ZDV/3TC/EFV and TDF/FTC/EFV further research is needed.

Keyphrases

hiv infected
antiretroviral therapy
open label
case report
human immunodeficiency virus
double blind
placebo controlled
randomized controlled trial
young adults
study protocol
childhood cancer