Comparison of toxin-antitoxin expression among drug-susceptible and drug-resistant clinical isolates of Mycobacterium tuberculosis.

Hossein Kazemian Hamid HeidariJalil Kardan-YamchiSobhan GhafourianIraj PakzadEbrahim KouhsariHasan ValadbeigiNourkhoda Sadeghifard

Published in: Advances in respiratory medicine (2021)

In this study, there was significant overexpression of mazE6 in drug-susceptible isolates. As well, mazF3 and F6 were overexpressed in drug-resistant isolates when compared with the standard strain. The changes in expression levels of MazEF6 associated genes were greater than that of MazEF3 in both groups of isolates.

Keyphrases

drug resistant
multidrug resistant
acinetobacter baumannii
mycobacterium tuberculosis
poor prognosis
genetic diversity
escherichia coli
cell proliferation
long non coding rna
adverse drug
drug induced
emergency department
dna methylation
pulmonary tuberculosis
bioinformatics analysis