Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors.

Rachel E SanbornMichael J PishvaianMargaret K CallahanAmy WeiseBranimir I SikicOsama RahmaDaniel C ChoNaiyer A RizviMario SznolJose LutzkyJulie E BaumanRhonda L BittingAlexander StarodubAntonio JimenoDavid A ReardonThomas KaleyFabio IwamotoJoachim M BaehringDeepa S SubramaniamJeanny B Aragon-ChingThomas R HawthorneTracey RawlsMichael YellinTibor Keler

Published in: Journal for immunotherapy of cancer (2022)

NCT02335918.

Keyphrases

open label
nk cells
randomized controlled trial
clinical trial
study protocol