Expression and role of nicotinic acetylcholine receptors during midbrain dopaminergic neuron differentiation from human induced pluripotent stem cells.
Takeshi KatoKaneyasu NishimuraMasahiro HiraoShun ShimohamaKazuyuki TakataPublished in: Neuropsychopharmacology reports (2023)
Our findings suggest that stimulating the α6 nAChR subunit on hiPSC-derived mDA neurons may induce neuronal maturation that is biased toward SNC DA neurons.