Plasma-Generated Poly(allyl alcohol) Antifouling Coatings for Cellular Attachment.
Lucy M WatkinsAdam Fraser LeeJames W B MoirKaren WilsonPublished in: ACS biomaterials science & engineering (2016)
Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energy-efficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.
Keyphrases
- biofilm formation
- escherichia coli
- pseudomonas aeruginosa
- staphylococcus aureus
- alcohol consumption
- candida albicans
- endothelial cells
- room temperature
- tissue engineering
- mass spectrometry
- cystic fibrosis
- pluripotent stem cells
- gold nanoparticles
- wound healing
- carbon nanotubes
- solid phase extraction
- induced pluripotent stem cells
- tandem mass spectrometry