Expression and DNA methylation profiles of EZH2-target genes in plasma exosomes and matched primary tumor tissues of the patients with diffuse large B-cell lymphoma.

I C BarısS HacıogluN S TurkG O CetınS ZencırG BagcıVildan Caner

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2020)

This study showed that plasma exosomes might preferably package certain target molecules from primary tumors and the exosomes containing dual methylated DNAs of CDKN2A and CDKN2B, or CDKN1B transcript may contribute to DLBCL pathogenesis.

Keyphrases

diffuse large b cell lymphoma
mesenchymal stem cells
dna methylation
epstein barr virus
stem cells
genome wide
gene expression
poor prognosis
long non coding rna
bone marrow
rna seq
long noncoding rna
binding protein
copy number
single cell
genome wide identification