A Randomized Trial of Closed-Loop Insulin Delivery Postpartum in Type 1 Diabetes.
Lois E DonovanDenice S FeigPatricia LemieuxHelen R MurphyRhonda C BellRonald J SigalJosephine HoHeidi VirtanenSusan CrawfordJennifer M YamamotoPublished in: Diabetes care (2023)
Women randomized to closed-loop insulin delivery postpartum had less hypoglycemia than those randomized to sensor-augmented pump therapy. There were no safety concerns. These findings are reassuring for use of closed-loop insulin delivery postpartum because of its potential to reduce hypoglycemia.
Keyphrases
- type diabetes
- glycemic control
- double blind
- open label
- placebo controlled
- phase iii
- insulin resistance
- cardiovascular disease
- phase ii
- clinical trial
- randomized controlled trial
- weight loss
- mesenchymal stem cells
- bone marrow
- adipose tissue
- smoking cessation
- study protocol
- breast cancer risk
- virtual reality
- replacement therapy