Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions.
Steffen RickeltCharlene CondonMiyeko D ManaCharlie WhittakerChristina PfirschkeJatin RoperDeepa T PatilIan BrownAnthony R MattiaLawrence ZukerbergQing ZhaoRunjan ChettyGregory Y LauwersAzfar NeyazLieve G J LeijssenKatherine BoylanOmer H YilmazVikram DeshpandeRichard O HynesPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Muscularis mucosae-based AGRN immunostaining is a novel biomarker to distinguish SSL from HP, TSA, and TA, with a specificity of 97.1% and sensitivity of 98.9% and can assist in diagnosis of morphologically challenging colonic polyps.
Keyphrases