Evaluation of an oral sodium bicarbonate protocol for high-dose methotrexate urine alkalinization.

Rachel D Heisler Jordan J KellySara Abedinzadegan AbdiJennifer L HawkerLeanne G FongJanet L QuonJosee Z RiouxJennifer C Y Jupp

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)

The results of this study indicate that the AHS PO sodium bicarbonate protocol was no different in time to methotrexate clearance or rates of increased serum creatinine when compared to IV sodium bicarbonate.

Keyphrases

high dose
randomized controlled trial
low dose
stem cell transplantation
metabolic syndrome
uric acid