Significant cognitive decline after VIM or cZi/PSA DBS in ET patients appears to be rare. Future prospective randomized controlled trials are needed to meticulously study the effect of the location, laterality, and stimulation parameters of the active contacts on cognitive outcomes while considering possible medication change post-DBS, timing, standard neuropsychological battery, practice effects, the timing of assessment, and effect size as potential confounders.
Keyphrases
- deep brain stimulation
- cognitive decline
- parkinson disease
- mild cognitive impairment
- obsessive compulsive disorder
- end stage renal disease
- newly diagnosed
- healthcare
- randomized controlled trial
- prostate cancer
- ejection fraction
- primary care
- chronic kidney disease
- current status
- clinical trial
- metabolic syndrome
- climate change
- adipose tissue
- glycemic control