Association of quantitative CT lung density measurements and lung function decline in World Trade Center workers.
Xiaoyu LiuAnthony P ReevesKatherine AntoniakRaúl San José EstéparJohn T DoucetteYunho JeonJonathan WeberDongming XuJuan C CeledónRafael E de la HozPublished in: The clinical respiratory journal (2020)
Longitudinal FEV1 decline in this cohort, known to be associated with QCT proximal airway inflammation metric, is also associated with QCT indicators of increased and decreased lung density. The improved FEV1 trajectory did not seem to be associated with lung density metrics.