Arterial stiffness in elderly patients with normotension and hypertension in Brazil.
Guilherme Silva de MendonçaDenis Fabiano de SouzaAna Cláudia de Alvarenga Cunha BrunelliCristina Ila de Oliveira PeresErcilhana Gonçalves Batista FreitasGabriela Nolasco LacerdaMichelle Caixeta DornelesAldo José PeixotoSebastião Rodrigues Ferreira FilhoPublished in: Journal of clinical hypertension (Greenwich, Conn.) (2018)
Data on arterial stiffness in older populations, according to blood pressure (BP) levels, are scarce in Brazil. The objective of this study was to establish reference values for core measures of arterial stiffness, including carotid-femoral pulse wave velocity (cf-PWV) and aortic augmentation index (AIx), in a cohort of older individuals with normotension (NT) and hypertension. Cross-sectional analysis was performed with applanation tonometry data from 1192 patients aged 60 years or older. The authors classified patients according to their BP levels as having NT, controlled hypertension (CH), and uncontrolled hypertension (UH). The cf-PWV values were 9.11 ± 0.16 m/s (NT), 9.12 ± 0.18 m/s (CH), and 9.42 ± 2.2 m/s (UH) (P < 0.005; UH vs NT and CH). The AIx was 33.3% for the entire cohort and similar across all groups. The cf-PWV increased with age but reached a ceiling at 75 years. Compared with men, women had a higher AIx but similar cf-PWV levels. In conclusion, the markers of arterial stiffness were similar among individuals with NT/CH and higher among individuals with UH.
Keyphrases
- blood pressure
- hypertensive patients
- cystic fibrosis
- end stage renal disease
- heart rate
- ejection fraction
- cross sectional
- newly diagnosed
- chronic kidney disease
- middle aged
- physical activity
- prognostic factors
- type diabetes
- big data
- left ventricular
- polycystic ovary syndrome
- weight loss
- coronary artery
- metabolic syndrome
- arterial hypertension
- ionic liquid
- breast cancer risk