Perspective of Adults With Neurofibromatosis 1 and Cutaneous Neurofibromas: Implications for Clinical Trials.

Ashley CannonDominique C PichardPamela L WoltersSarah AdsitGregg EricksonAndrés J Lessing Tanja DudenbostelWhitney NarmoreClaas RöhlTena RosserBrigitte C WidemannJaishri O BlakeleyScott R Plotkinnull null

Published in: Neurology (2021)

Most adults with NF1 are willing to consider experimental therapies for treatment of cNF. These data will guide the design of patient-centered clinical trials for adults with cNF.

Keyphrases

clinical trial
signaling pathway
phase ii
electronic health record
oxidative stress
open label
pi k akt
phase iii
randomized controlled trial
double blind
study protocol
combination therapy
cell proliferation
smoking cessation