The Role of Resveratrol in Human Male Fertility.
Laura Maria MongioìSarah PerelliRosita Angela CondorelliFederica BarbagalloAndrea CrafaRossella CannarellaSandro La VigneraAldo Eugenio CalogeroPublished in: Molecules (Basel, Switzerland) (2021)
Resveratrol (RSV) (3,4',5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.
Keyphrases
- endothelial cells
- human health
- induced pluripotent stem cells
- risk assessment
- cardiovascular disease
- blood pressure
- type diabetes
- pluripotent stem cells
- metabolic syndrome
- respiratory tract
- climate change
- insulin resistance
- weight loss
- adipose tissue
- physical activity
- childhood cancer
- weight gain
- high fat diet induced
- subarachnoid hemorrhage
- blood brain barrier
- cardiovascular events
- arterial hypertension