Cost-Effectiveness of Closed-Loop Automated Insulin Delivery Using the Cambridge Hybrid Algorithm in Children and Adolescents with Type 1 Diabetes: Results from a Multicenter 6-Month Randomized Trial.

D Steven Fox Julia Ware Charlotte K BoughtonJanet M AllenMalgorzata E WilinskaMartin TauschmannLouise DenvirAjay ThankamonyFiona CampbellR Paul Wadwa Bruce A BuckinghamNikki DavisLinda A DiMeglioNelly MaurasRachel Elizabeth Jane BesserAtrayee GhatakStuart A WeinzimerLauren G KanapkaCraig KollmanJudy SibayanRoy W BeckKorey K Hood Roman Hovorka

Published in: Journal of diabetes science and technology (2024)

For children and adolescents with T1D on insulin pump therapy, AID using the Cambridge algorithm appears cost-effective below a £20 000/QALY threshold (United Kingdom) and cost saving (United States).

Keyphrases

machine learning
deep learning
type diabetes
glycemic control
cross sectional
neural network
high throughput
clinical trial
double blind
skeletal muscle
metabolic syndrome
insulin resistance
smoking cessation