Stereotactic Radiosurgery for Vestibular Schwannoma in Neurofibromatosis Type 2: An International Multicenter Case Series of Response and Malignant Transformation Risk.

Othman Bin-AlamerAndrew FaramandNorah A AlarifiZhishuo WeiArka N MallelaVictor M LuAhmed M NabeelWael A RedaSameh R TawadrosKhaled AbdelkarimAmr M N El-ShehabyReem M EmadSelcuk PekerYavuz SamanciCheng-Chia LeeHuai-Che YangViolaine DelabarDavid MathieuManjul TripathiKathryn Nicole KearnsAdomas BuneviciusJason P SheehanTomas ChytkaRoman LiscakNuria Martínez MorenoRoberto Martínez ÁlvarezInga S GrillsJacob S ParzenChristopher P CifarelliAzeem A RehmanHerwin SpeckterAjay NiranjanL Dade LunsfordHussam Abou-Al-Shaar

Published in: Neurosurgery (2023)

Although the absolute volumetric tumor progression rate was 48% at 15 years, the rate of FFAT related to VS was 75% at 15 years after SRS. None of the patients with NF2-related VS developed a new radiation-related neoplasm or malignant transformation after SRS.

Keyphrases

signaling pathway
radiation therapy
cross sectional
radiation induced
nuclear factor