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Deficiency of Histone Methyltransferase SET Domain-Containing 2 in Liver Leads to Abnormal Lipid Metabolism and HCC.

Xue-Jing LiQing-Lan LiLin-Gao JuChen ZhaoLan-Shen ZhaoJia-Wen DuYan WangLing ZhengBao-Liang SongLian-Yun LiLi LiMin Wu
Published in: Hepatology (Baltimore, Md.) (2021)
We revealed the roles of Setd2 in HCC and the underlying mechanisms in regulating cholesterol homeostasis and c-Jun/AP-1 signaling.
Keyphrases
  • dna methylation
  • transcription factor
  • low density lipoprotein
  • fatty acid
  • replacement therapy
  • gene expression