SIAH2 is Expressed in Adipocyte Precursor Cells and Interacts with EBF1 and ZFP521 to Promote Adipogenesis.

Thanh N DangJessica L TaylorGail KilroyYongmei YuDavid H BurkZ Elizabeth Floyd

Published in: Obesity (Silver Spring, Md.) (2020)

Siah2 is expressed in PDGFRα+ adipocyte precursor cells and is linked to precursor cell commitment to adipogenesis by interacting with EBF1 and ZFP521 proteins to target the antiadipogenic ZFP521 for degradation.

Keyphrases

induced apoptosis
cell cycle arrest
adipose tissue
insulin resistance
fatty acid
endoplasmic reticulum stress
stem cells
signaling pathway
type diabetes
cell therapy
skeletal muscle
mesenchymal stem cells
binding protein