Data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI.

Adam K FeatherstoneJames P B O'ConnorRoss A LittleYvonne WatsonSue CheungMuhammad BaburKaye J WilliamsJulian C MatthewsGeoffrey J M Parker

Published in: Magnetic resonance in medicine (2017)

The proposed method locates similar regions to the previous published method of binarization of DCE/OE-MRI enhancement, but renders a finer segmentation of intra-tumoral oxygenation and perfusion. This could aid in understanding the tumor microenvironment and its heterogeneity. Magn Reson Med 79:2236-2245, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Keyphrases

contrast enhanced
magnetic resonance
magnetic resonance imaging
diffusion weighted imaging
computed tomography
high resolution
randomized controlled trial
convolutional neural network
mass spectrometry
drug induced