Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study).

Iain Robert Louis Kean John Alexander ClarkZhenguang ZhangEsther DaubneyDeborah WhitePaloma Ferrando-VivasGema MillaBrian CuthbertsonJohn PappachanNigel KleinPaul MounceyKathy RowanJohn MyburghTheodore GouliourisStephen BakerJulian ParkhillNazima Pathannull Arctic Research Team

Published in: Gut (2024)

Short interventions of SDD caused a shift in the microbiome but not of the AMR gene pool in critically ill children at the end mechanical ventilation, compared with standard antimicrobial therapy.

Keyphrases

antimicrobial resistance
mechanical ventilation
acute respiratory distress syndrome
intensive care unit
study protocol
young adults
climate change
physical activity
copy number
randomized controlled trial
stem cells
open label
gene expression
risk factors
genome wide identification
replacement therapy