Informing antimicrobial management in the context of COVID-19: understanding the longitudinal dynamics of C-reactive protein and procalcitonin.
Damien Keng Yen MingAshleigh C MyallBernard HernandezAndrea Y WeißeRobert L PeachMauricio BarahonaTimothy M RawsonAlison H HolmesPublished in: BMC infectious diseases (2021)
Both the absolute CRP concentration and the trajectory during the first week of hospital admission are important factors predicting microbiology culture positivity and outcome in patients hospitalised with COVID-19. Further work is needed to describe the role of PCT for co-infection. Understanding relationships of these biomarkers can support development of risk models and inform optimal antimicrobial strategies.
Keyphrases
- coronavirus disease
- sars cov
- end stage renal disease
- staphylococcus aureus
- newly diagnosed
- ejection fraction
- chronic kidney disease
- emergency department
- healthcare
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- respiratory syndrome coronavirus
- study protocol
- adverse drug
- electronic health record