CYTOPLASMIC-MEMBRANE EGFR PREDICTS EXPANDED RAS MUTATION STATUS IN COLORECTAL CARCINOMAS?

Thiago David Alves Pinto Thaís David das Neves Alves Sebastião Alves Pinto Enio Chaves de Oliveira

Published in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2021)

The cytoplasmic-membrane analysis of the EGFR expression stratified into "positive", "negative" and "uncertain" predicts mutational status of the RAS in 51.7% of the cases (p<0.001), with 86.1% of accuracy.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
poor prognosis
wild type
high grade
binding protein
long non coding rna