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The Effectiveness of ddPCR for Detection of Point Mutations in Poor-Quality Saliva Samples.

Petra RiedlovaDagmar KramnaSilvie OstrizkovaHana TomaskovaVitezslav Jirik
Published in: Healthcare (Basel, Switzerland) (2022)
This study verified the applicability of ddPCR as a sensitive and robust method of genetic diagnostic testing even from low-quality saliva isolates. This makes it potentially suitable for a wide range of applications and facilitates the performance of large epidemiological studies, even if sampling or sample processing is suboptimal.
Keyphrases
  • randomized controlled trial
  • systematic review
  • genome wide
  • label free
  • case control
  • genetic diversity