Immunotherapeutic Properties of Dexmedetomidine on Pain Management and Cardiovascular Function in Videolaparoscopic Cholecystectomies: A Randomized, Two-Arm, Double-Blinded, Placebo-Controlled Trial.

Gustavo Nascimento Silva Virna Guedes Alves BrandãoMarcelo Vaz PerezSandoval Lage SobrinhoJoão Gabriel de Cerqueira Campos VillardiPriscilla Mendonça do SacramentoLuiz Claudio Pereira RibeiroRossano Kepler Alvim Fiorelli

Published in: Surgical innovation (2024)

Dexmedetomidine provided anti-inflammatory activity, sympatholytic effect and analgesia with cardiovascular safety. It reinforces the therapeutic nature of highly selective α2-adrenergic agonists when combined within anesthetic interventions.

Keyphrases

pain management
chronic pain
cardiac surgery
physical activity
double blind
study protocol
randomized controlled trial
postoperative pain