Progranulin and beta-catenin in psoriasis: An immunohistochemical study.

Azza Gaber Antar FaragMohamed Abdalmoneim ShoaibRehab Mounir SamakaAsmaa Gaber AbdouMarwa Mahmoud MandourReda Abdel Latif Ibrahim

Published in: Journal of cosmetic dermatology (2019)

Progranulin has a pro-inflammatory effect in the psoriasis pathogenesis, which could be mediated through a decreasing β-catenin expression in psoriasis. PGRN may be used as a target for immunotherapy in psoriasis management program.

Keyphrases

epithelial mesenchymal transition
atopic dermatitis
cell proliferation
poor prognosis
quality improvement