Clinical implementation of pre-treatment DPYD genotyping in capecitabine-treated metastatic breast cancer patients.

Chara StavrakaAthanasios PouptsisLeroy OkontaKaren DeSouzaPhilip CharltonMatthaios KapirisAnthony MarinakiEleni KarapanagiotouDionysis Papadatos-PastosJanine Mansi

Published in: Breast cancer research and treatment (2019)

Prospective DPYD genotyping can be successfully implemented in routine clinical practice and can reduce the risk of severe fluoropyrimidine toxicities.

Keyphrases

clinical practice
genome wide
high throughput
small cell lung cancer
squamous cell carcinoma
healthcare
primary care
genetic diversity
quality improvement
randomized controlled trial
phase ii study
dna methylation
clinical trial
metastatic breast cancer
newly diagnosed
smoking cessation