Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants.
Chia-Ling KuoLuke C PillingJanice C AtkinsJane A H MasoliJoão C DelgadoChristopher TignanelliGeorge A KuchelDavid MelzerKenneth B BeckmanMorgan E LevinePublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)
PhenoAge measured in 2006-2010 was associated with COVID-19 severity outcomes more than 10 years later. These associations were partly accounted for by prevalent chronic diseases proximate to COVID-19 infection. Overall, our results suggest that aging biomarkers, like PhenoAge may capture long-term vulnerability to diseases like COVID-19, even before the accumulation of age-related comorbid conditions.