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Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1.

Qudong LuYang YangHengshuai ZhangCheng ChenJiang ZhaoZhenxing YangYi FanLongkun LiHuan FengJingzhen ZhuShanhong Yi
Published in: Drug design, development and therapy (2021)
Activation of GPR18 by RvD2 alleviated hyperalgesia and improved bladder function, possibly by inhibiting TRPV1 in rats with CYP-induced cystitis.
Keyphrases
  • neuropathic pain
  • spinal cord injury
  • high glucose
  • diabetic rats
  • signaling pathway
  • low dose
  • fatty acid
  • spinal cord
  • high dose
  • drug induced
  • oxidative stress
  • endothelial cells
  • pain management