Delphinidin induces autophagic flux blockage and apoptosis by inhibiting both multidrug resistance gene 1 and DEAD-box helicase 17 expressions in liver cancer cells.
Shenghui SunKun XuMingjing YanJu CuiKaiyi ZhuYao YangXiaoyi ZhangWeiqing TangXiuqing HuangLin DouBeidong ChenYajun LinXiyue ZhangYong ManJian LiTao ShenPublished in: The Journal of pharmacy and pharmacology (2022)
Delphinidin has a strong anti-tumour effect by inducing tumour cell autophagic flux blockage and apoptosis by inhibiting of both MDR1 and DDX17 expression.
Keyphrases
- cell death
- cell cycle arrest
- oxidative stress
- endoplasmic reticulum stress
- signaling pathway
- poor prognosis
- binding protein
- single cell
- multidrug resistant
- genome wide
- cell therapy
- copy number
- transcription factor
- pi k akt
- long non coding rna
- mesenchymal stem cells
- cell proliferation
- genome wide identification
- genome wide analysis